Fatto generale: 16 is the minimum age that one can drop out of school in most states of the US (however, restrictions apply and vary depending on state).
Fatto matematico: 16 is the hexadecimal system, a common number system used in computer programming, uses 16 digits where the last 6 are usually represented by letters: 0,1,2,3,4,5,6,7,8,9,A,B,C,D,E,F.
Trivia: 16 is the number of teams that qualified for the finals of the FIFA World Cup from 1934 through 1978 (although for various reasons, only 15 competed in the 1938 and 1950 finals).
Data storica: January 16th is the day in 1942 that Crash of TWA Flight 3, killing all 22 aboard, including film star Carole Lombard.