Fatto generale: 16 is the minimum age for getting an adult job in most states and provinces across the globe.
Fatto matematico: 16 is the first number to be the aliquot sum of a lesser number; 12, it is also the aliquot sum of the greater number; the discrete semiprime, 26.
Trivia: 16 is the number of teams that qualified for the finals of the FIFA World Cup from 1934 through 1978 (although for various reasons, only 15 competed in the 1938 and 1950 finals).
Data storica: January 16th is the day in 1492 that the first grammar of the Spanish language is presented to Queen Isabella I.