Fatto generale: 5363 is a number for which we're missing a fact (submit one to numbersapi at google mail!).
Fatto matematico: 5363 is an unremarkable number.
Trivia: 5363 is an uninteresting number.
Data storica: September 6th is the day in 2009 that the ro-ro ferry SuperFerry 9 sinks off the Zamboanga Peninsula in the Philippines with 971 persons aboard; all but ten are rescued.