Fatto generale: 4452 is a number for which we're missing a fact (submit one to numbersapi at google mail!).
Fatto matematico: 4452 is a boring number.
Trivia: 4452 is an uninteresting number.
Data storica: March 9th is the day in 1990 that Dr. Antonia Novello is sworn in as Surgeon General of the United States, becoming the first female and Hispanic American to serve in that position.