Fatto generale: 4216 is a number for which we're missing a fact (submit one to numbersapi at google mail!).
Fatto matematico: 4216 is an octagonal pyramidal number.
Trivia: 4216 is a boring number.
Data storica: July 17th is the day in 1981 that a structural failure leads to the collapse of a walkway at the Hyatt Regency in Kansas City, Missouri killing 114 people and injuring more than 200.