Fatto generale: 16 is the minimum age that one can drop out of school in most states of the US (however, restrictions apply and vary depending on state).
Fatto matematico: 16 is a centered pentagonal number.
Trivia: 16 is the minimum age for getting an adult job in most states and provinces across the globe.
Data storica: January 16th is the day in 1900 that the United States Senate accepts the Anglo-German treaty of 1899 in which the United Kingdom renounces its claims to the Samoan islands.